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. 2014 Jun 1;2:16. doi: 10.1186/2052-8426-2-16

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© Donzelli et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Schematic representation of the mechanisms of action of chemoresistance-associated miRNAs. MicroRNAs have been demonstrated to be involved in the modulation of chemoresistance of cancer cells trough the regulation of the expression of different target genes involved in the control of apoptosis, or multi drug resistance, or DNA repair or drug metabolism.