Figure 4.
Titer of autoantibody against p53 in human sera by ELISA. The range of antibody titers to p53 was expressed as optical density (OD) obtained from ELISA. The mean + 2SD of NHS was shown in relationship to all serum samples. Titer of anti-p53 in SLE serum was much higher than that in NHS (P < 0.01). The cutoff value line for positive samples is indicated in the figure.