Table 1.
Clinical and serological characteristics of pSS patients.
| Features | 1pSS Abs− | 2pSS Abs+ | P * |
|---|---|---|---|
| (n = 29) | (n = 23) | I-II | |
| Age, mean ± SD years | 56 ± 12 | 56 ± 13 | 0.873 |
| Schirmer's I test (mm/5 min), mean ± SD | 3.17 ± 1.20 | 1.25 ± 1.12 | <0.0001 |
| Unstimulated salivary flow (mL/15 min), mean ± SD | 1.22 ± 0.20 | 0.83 ± 0.39 | 0.002 |
| Biopsy focus score | 1.17 (1/2) | 2.40 (1/3) | <0.0001 |
| (number of lymphocytic foci/4 mm2), mean (min/max) | |||
| Anti-SSA+, n (%) | 0 (0) | 6 (26) | |
| Anti-SSB+, n (%) | 0 (0) | 2 (9) | |
| BAFF, mean ± SD, ng/mL | 4230 (1748) | 5014 (2518) | 0.187 |
| Anti-SSA/SSB+, n (%) | 0 (0) | 15 (65) | |
| ESSPRI, mean (min/max) | 8.39 (6/10) | 9.1 (7/10) | 0.075 |
| ESSDAI, mean (min/max) | 24.83 (21/30) | 33.50 (27/39) | <0.0001 |
*Mann-Whitney test. 1pSS Abs−: pSS patients without anti-SSA/SSB; 2pSS Abs+: pSS patients with anti-SSA and/or anti-SSB. ESSDAI: EULAR Sjögren's syndrome disease activity index; ESSPRI: EULAR Sjögren's syndrome patient reported index.