Table 4.
Distribution of CD8+ lymphocyte subpopulations in peripheral blood of pSS patients and controls.
| Patients | 1I-controls | 2II-pSS Abs− | 3III-pSS Abs+ | P * | P * | P * |
|---|---|---|---|---|---|---|
| I-II | I-III | II-III | ||||
| CD8+ lymphocyte population | ||||||
| CD8highCD57+CD27+ | ||||||
| %4 | 5.306 ± 3.899 | 5.329 ± 5.431 | 8.239 ± 8.239 | NS | NS | 0.032 |
| A. count# | 34.26 ± 29.11 | 27.05 ± 33.57 | 42.59 ± 33.12 | NS | NS | 0.011 |
| CD8highCD57+CD27− | ||||||
| %4 | 22.67 ± 13.33 | 25.52 ± 17.42 | 27.40 ± 19.55 | NS | NS | NS |
| A. count# | 150.6 ± 119.7 | 143.4 ± 157.7 | 155.2 ± 136.8 | NS | NS | NS |
| CD8highCD57−CD27+ | ||||||
| %4 | 59.13 ± 17.54 | 46.51 ± 22.00 | 47.16 ± 22.29 | 0.026 | NS | NS |
| A. count# | 387.3 ± 211.4 | 227.9 ± 186.6 | 224.8 ± 129.3 | 0.0003 | 0.005 | NS |
| CD8highCD57−CD27− | ||||||
| %4 | 13.10 ± 8.112 | 22.60 ± 15.37 | 17.18 ± 11.20 | 0.024 | NS | NS |
| A. count# | 85.79 ± 73.99 | 119.1 ± 126.7 | 99.46 ± 85.96 | NS | NS | NS |
| CD8+FoxP3 | ||||||
| %5 | 10.59 ± 15.16 | 5.881 ± 6.673 | 6.498 ± 7.939 | NS | NS | NS |
| A. count# | 91.42 ± 126.1 | 51.19 ± 86.72 | 50.49 ± 60.37 | NS | NS | NS |
1I group: healthy controls; 2II group: pSS patients without anti-SSA/SSB; 3III group: pSS patients with anti-SSA and/or anti-SSB; %4: proportion of all CD8high lymphocytes; %5: proportion of all CD8+ lymphocytes. A. count#: absolute count of cells in 1 μL of blood. *Mann-Whitney test. NS: not significant.