Table 3.

Factors associated with the use of antipsychotic medication in the Northern Finland Birth Cohort 1966.

Factors	Effect of higher use of antipsychotic medication
Sex	Females used more often medication [36]
Age at onset of psychosis	No association [36]
Psychiatric hospital treatment	Increased need of hospital treatment [36]
Clinical measures (PANSS, CGI, SOFAS, and remission)	Poorer clinical and social outcome [36]
Occupational functioning	Higher rate of disability pensions and lower rate of employment [36]
Brain volume loss	Increased brain loss [37]
Change of cognition	Decline of verbal learning and memory [38]
Suicidal ideation	No association when symptoms of depression and anxiety were controlled for [39]
Hyperlipidemia	Increased risk of hyperlipidemia [40]

PANSS = Positive and Negative Syndrome Scale, CGI = Clinical Global Impression, and SOFAS = Social and Occupational Functioning Assessment Scale.