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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: J Acquir Immune Defic Syndr. 2015 May 1;69(1):52–60. doi: 10.1097/QAI.0000000000000549

Figure 1. T cell subsets and expression of activation markers in PBMC.

Figure 1

Figure 1

Flow cytometry of T cells gated on CD3+CD4+ T cells (panels A and B) or CD3+CD8+ T cells (panels C and D) from representative uninfected (HIV−) and HIV-infected (HIV+) subjects. Panels A and C show density contour plots of CCR7 and CD45RA expression in CD4+ T cells (A & B) and CD8+ T cells (C & D). T cell subsets are defined as Naïve (CD3+ CD4/8+ CD45RA+ CCR7+); TCM (CD3+ CD4/8+ CD45RA− CCR7+); TEMRO (CD3+ CD4/8+ CD45RA−CCR7−); and TEMRA (CD3+ CD4/8+ CD45RA+ CCR7−). Percentage of cells based on FMO controls are shown for each quadrant. Activation markers CD28, CD38, and HLA DR are shown (B & D) as overlaid histogram plots for each subset.