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In vitro safety and toxicity of GC-P4 hydrogel. (a) MTT assays indicated no difference in percent viability in VK2/E6E7 cell after treatment with GC solutions. (b) No difference between % viability of Lactobacillus crispatus after treatment with different concentration of GC compared to non-treated cells. (c) VK2/E6E7 cell lines retained their ability to form colonies after treatment with 5% GC and GC-P4200μg gel compared to P4200μg alone, Gynol II®, and Crinone®200μg.
