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. 2015 Mar 25;106(5):497–504. doi: 10.1111/cas.12647

Table 2.

Equations predicting docetaxel clearance for European/American and Japanese populations

Authors Equations predicting docetaxel clearance ωCL (%)
Bruno et al.18 CL = BSA (22.1 − 3.55 AAG − 0.095 AGE + 0.225 ALB) (1 − 0.334 HEP) 33
Tanigawara et al.19 CL = BSA (37.6 − 6.41 AAG − 0.191 AGE + 0.0436 ALB) (1 − 0.209 HEP) 25

AAG, α1-acid glycoprotein level (g/L); ALB, albumin level (g/L); AGE (years); BSA, body surface area (m2); CL, total body clearance (L/h); HEP, complication of hepatic dysfunction indicated by HEP = 1 (presence) or HEP = 0 (absence).