Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Apr 1;106(5):550–558. doi: 10.1111/cas.12654

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 The Authors. Cancer Science published by Wiley Publishing Asia Pty Ltd on behalf of Japanese Cancer Association.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

PMC Copyright notice

Fig 2 — ERAP suppresses the cell growth induced by the crosstalk between E2 and insulin-like growth factor 1 (IGF-1). (a, b) MTT assays evaluating the inhibitory effect of ERAP on the growth of MCF-7 (a) and BT-474 (b) cells by 10 nM E2 and/or 50 ng/mL IGF-1 stimulation. These data represent the mean ± SD of three independent experiments (*P < 0.05; **P < 0.01; ***P < 0.001). (c) Flow cytometric analyses showing the effect of ERAP and tamoxifen on the cell cycle in the presence of E2 and IGF-1 in MCF-7 cells.