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Treatment with 2-DG blocks the effects of c-Myc–LDHA axis on tumor growth and progression in pancreatic cancer cells in vitro. In the presence of 2-DG, cell viability of AsPC-1 cells (a) and SW1990 cells (b), cell migration (c) and invasion (d) abilities were measured after c-Myc was silenced. In the presence of 2-DG, cell viability of AsPC-1 cells (e) and SW1990 cells (f), cell migration (g) and invasion (h) abilities were measured after LDHA was silenced
