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. 2015 Jun 1;10(6):e0128474. doi: 10.1371/journal.pone.0128474

Table 4. Multivariate regression analysis using area under the curve of pain-related BA3, BA6 and BA24 activation in the left hemisphere as predictors of pain and distress ratings in Hypnosis condition (step-1) and after entering SHCS scores as a covariate (step-2).

Pain Rating Distress Rating
BA Region Estimate SE P Estimate SE P
Control 1 Control 7
Intercept 5.301 0.44 12.05 <.0001 - - - -
BA3-RH 0.215 0.071 3.04 0.007 - - - -
Control 2 Control 8
Intercept 5.154 0.606 8.51 <.0001 - - - -
SHCS 0.055 0.152 0.36 0.721 - - - -
BA3-RH 0.217 0.072 2.99 0.008 - - - -
Hypoalgesia 3 Hypoalgesia 9
Intercept 3.576 0.422 8.47 <.0001 3.033 0.401 7.56 <.0001
BA3-LH 0.408 0.19 2.15 0.046 0.193 0.181 1.07 0.3
BA3-RH 0.279 0.208 1.34 0.198 0.466 0.198 2.35 0.031
Hypoalgesia 4 Hypoalgesia 10
Intercept 3.262 0.869 3.76 0.0017 3.572 0.815 4.38 0.0005
SHCS 0.097 0.231 0.42 0.682 -0.166 0.217 -0.76 0.457
BA3-LH 0.445 0.214 2.08 0.054 0.13 0.201 0.65 0.528
BA3-RH 0.268 0.215 1.24 0.231 0.485 0.202 2.4 0.029
Hyperalgesia 5 Hyperalgesia 11
Intercept 5.447 0.718 7.58 <.0001 - - - -
BA3-LH 0.272 0.087 3.12 0.006 - - - -
Hyperalgesia 6 Hyperalgesia 12
Intercept 4.22 0.604 6.99 <.0001 - - - -
SHCS 0.621 0.151 4.1 0.0007 - - - -
BA3-LH 0.229 0.065 3.55 0.002 - - - -

1 Step-1: F(1,19) = 9.27, p = 0.007; R-Square = 0.34, Adj. R-Square = 0.30

2 Step-2 entering SHCS: F(2,19) = 4.48, p = 0.0274; R-Square = 0.34, Adj. R-Square = 0.27

3 Step-1: F(2,19) = 12.67, p = 0.0004; R-Square = 0.590, Adj. R-Square = 0.55

4 Step-2 entering SHCS: F(3,19) = 8.10, p = 0.0017; R-Square = 0.60, Adj. R-Square = 0.53

5 Step-1: F(1,19) = 9.70, p = 0.006; R-Square = 0.35, Adj. R-Square = 0.31

6 Step-2 entering SHCS: F(2,19) = 17.52, p<.0001; R-Square = 0.67, Adj. R-Square = 0.63

7 Non Significant

8 Non Significant

9 Step-1: F(2,19) = 12.36, p = 0.0005; R-Square = 0.59, Adj. R-Square = 0.54

10 Step-2: F(3,19) = 8.23, p = 0.0015; R-Square = 0.60, Adj. R-Square = 0.53

11 Non Significant

12 Non Significant;