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. 2015 Jun 1;10(6):e0128525. doi: 10.1371/journal.pone.0128525

Table 2. Clinico-pathological association of SOX9 immunostaining in all cancers.

Parameter Evaluable (n) SOX9 (%) P value
    negative weak moderate strong  
Total 7565 33 15 39 13
Tumor stage <0.0001
pT2 4921 32 14 40 15
pT3a 1725 34 18 37 11
pT3b 848 34 20 36 10
pT4 40 43 25 28 5
Gleason grade <0.0001
≤3+3 1741 38 11 37 14
3+4 4363 30 16 40 14
4+3 1115 34 20 36 10
≥4+4 306 38 19 32 11
Lymph node metastasis 0.04
N0 4233 32 17 39 13
N+ 371 36 18 37 9
Preoperative PSA level (ng/ml) <0.0001
<4 905 25 14 43 18
4–10 4597 31 15 41 14
>10–20 1487 37 18 33 12
>20 491 48 17 29 6
Surgical margin 0.01
negative 6053 32 15 39 14
positive 1374 37 16 36 12