Table 2. Clinico-pathological association of SOX9 immunostaining in all cancers.
Parameter | Evaluable (n) | SOX9 (%) | P value | |||
---|---|---|---|---|---|---|
negative | weak | moderate | strong | |||
Total | 7565 | 33 | 15 | 39 | 13 | |
Tumor stage | <0.0001 | |||||
pT2 | 4921 | 32 | 14 | 40 | 15 | |
pT3a | 1725 | 34 | 18 | 37 | 11 | |
pT3b | 848 | 34 | 20 | 36 | 10 | |
pT4 | 40 | 43 | 25 | 28 | 5 | |
Gleason grade | <0.0001 | |||||
≤3+3 | 1741 | 38 | 11 | 37 | 14 | |
3+4 | 4363 | 30 | 16 | 40 | 14 | |
4+3 | 1115 | 34 | 20 | 36 | 10 | |
≥4+4 | 306 | 38 | 19 | 32 | 11 | |
Lymph node metastasis | 0.04 | |||||
N0 | 4233 | 32 | 17 | 39 | 13 | |
N+ | 371 | 36 | 18 | 37 | 9 | |
Preoperative PSA level (ng/ml) | <0.0001 | |||||
<4 | 905 | 25 | 14 | 43 | 18 | |
4–10 | 4597 | 31 | 15 | 41 | 14 | |
>10–20 | 1487 | 37 | 18 | 33 | 12 | |
>20 | 491 | 48 | 17 | 29 | 6 | |
Surgical margin | 0.01 | |||||
negative | 6053 | 32 | 15 | 39 | 14 | |
positive | 1374 | 37 | 16 | 36 | 12 |