Table 3. Epitopes contained in the gastrointestinal-enzyme resistant 26-mer and 33-mer gluten peptides.
26-mer | FLQPQQPFPQQPQQPYPQQPQQPFPQ |
DQ2.5-glia-γ5 | ----QQPFPQQPQ------------- |
DQ2.5-glia-γ3 * | ---------QQPQQPYPQ-------- |
DQ2.5-glia-γ4c * | -----------------QQPQQPFPQ |
33-mer | LQLQPFPQPQLPYPQPQLPYPQPQLPYPQPQPF |
DQ2.5-glia-α1a | ----PFPQPQLPY-------------------- |
DQ2.5-glia-α1b | -----------PYPQPQLPY------------- |
DQ2.5-glia-α1b | ------------------PYPQPQLPY------ |
DQ2.5-glia-α2 | ------PQPQLPYPQ------------------ |
DQ2.5-glia-α2 | -------------PQPQLPYPQ----------- |
DQ2.5-glia-α2 | --------------------PQPQLPYPQ---- |
The sequences of the 26-mer and 33-mer peptide are shown. Underneath, the position of the immunogenic epitopes is denoted
*the epitopes DQ8-glia-γ1a and DQ8-glia-γ1b are identical to epitopes DQ2.5-glia-γ4c respectively DQ2.5-glia-γ3