. Author manuscript; available in PMC: 2015 Aug 1.

Published in final edited form as: Transl Res. 2014 Mar 4;164(2):110–121. doi: 10.1016/j.trsl.2014.02.004

Table IV.

Cumulative disease risk in the general population representation group and in first-degree relatives of individuals with T1D monitored for a 15-year period³⁵

Antibody		Cumulative disease risk, % (95% CI)
GAD Ab	IA2 Ab	General population group	First-degree T1D relative group
+	−	24 (9–38)	61 (48–74)
−	+	32 (12–51)	74 (61–88)
+	+	86 (60–100)	83 (69–97)

Abbreviations: Ab, antibody; CI, confidence interval; GAD, glutamic acid decarboxylase; IA, insulinoma antigen 2; T1D, type 1 diabetes.