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. Author manuscript; available in PMC: 2016 Jun 2.
Published in final edited form as: Annu Rev Biochem. 2015 Jan 26;84:739–764. doi: 10.1146/annurev-biochem-060614-034402

Figure 6. Structural basis for negative cooperativity in ligand binding to Drosophila. EGFR.

Figure 6

The unliganded (PDB ID 3I2T), singly-liganded (PDB ID 3LTG) and doubly-liganded (PDB ID 3LTF) dEGFR dimer. The structure of the doubly liganded human EGFR dimer (PDB ID 3NJP) is shown on the right.