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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Alcohol Clin Exp Res. 2015 May 14;39(6):962–968. doi: 10.1111/acer.12735

Figure 2.

Figure 2

Pharmacological characterization of GLIC/GlyR chimera. (a) Proton response curves for GLIC (blue) and chimera (purple) receptors. Dashes indicate EC10, ~pH 7.25 for the chimera. (b) Potentiation of chimera receptors by various concentrations of ethanol, measured as in Fig. 1, in the presence (lavender) and absence (purple) of 10 mM tricine to chelate environmental zinc. Tricine did not alter ethanol responses at any concentration tested. In a–b, errors are s.e.m., n = 2–7.