Table 1.
Correlation of HOTAIR and Plk1 up-regulation between Tumor and Non-Tumor (ratio ≥ 2) to clinico-pathological features of 13 HBV-related HCCs (Group B). AFP = α-fetoprotein Spearman's correlation coefficient (P value) shown in parenthesis.
Marker over-expression in Tumors | HOTAIR(+) | Plk1(+) | Group A vs. Group B |
---|---|---|---|
Presence of cirrhosis | −0.29 (.29) | −0.41 (.13) | 0.37 (.09) |
Tumor size > 50 mm | 0.28 (.29) | 0.27 (.32) | −0.20 (.36) |
Poor differentiation status (WHO classification) | 0.09 (.73) | −0.20 (.47) | 0.09 (.68) |
AFP > 200 ng/mL | 0.001 (.99) | 0.27 (.32) | 0.05 (.81) |
Microvascular invasion | 0.28 (.29) | 0.41 (.13) | −0.13 (.56) |
Portal neoplastic embolization | −0.1 (.72) | 0.35 (.19) | 0.03 (.90) |
Presence of satellite nodules | 0.57 (.02) | 0.06 (.80) | − 0.81 (.05) |