Figure 3.

CD3⁺ T cells infiltrate the corpus callosum of cuprizone-fed mice following Th17 cell transfer. Mice were killed 14 d after cessation of the cuprizone diet and T-cell transfer. CD3⁺ cells are occasionally observed in the corpus callosum of mice receiving either Th17 cells or cuprizone alone but are robustly present in those receiving both treatments. Representative images from two independent experiments. N = 3 mice per group. Scale bar, 50 μm.