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. 2015 Jun 3;35(22):8640–8652. doi: 10.1523/JNEUROSCI.2257-14.2015

Figure 5.

Figure 5.

Increased activation of Akt in Eed cKO nerves. Western blot analysis of lysates from control and Eed cKO sciatic nerves using indicated antibodies. A, Blots of 2 month nerves for p-AKT/AKT and blots of 4 month nerves for p-ERK/ERK, EGR2/actin, and PMP22/actin. Lanes of control and Eed cKO samples were taken from the same image of the same membrane. B, Quantification of Western blot. p-Akt/Akt; n = 7 per genotype (1 month, n = 3 per genotype; 2 month, n = 4 per genotype). p-ERK/ERK, EGR2/actin, and PMP22/actin; 4 month, n = 4 per genotype. Data: mean ± SD; ***p < 0.00001, *p < 0.05.