Table 2.
A list of top 30 proteins that are significantly regulated by KSR1 overexpression in the presence of etoposide
| Symbols | GeneIDs | Full descriptions | P value |
|---|---|---|---|
| OAS2 | 4939 | 2′-5′-oligoadenylate synthetase 2, 69/71 kDa | 3.18E−33 |
| MX1 | 4599 | MX dynamin-like GTPase 1 | 2.97E−32 |
| IFIT1 | 3434 | Interferon-induced protein with tetratricopeptide repeats 1 | 7.00E−31 |
| IFIT2 | 3433 | Interferon-induced protein with tetratricopeptide repeats 2 | 1.24E−29 |
| DDX58 | 23586 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 1.92E−24 |
| OAS3 | 4940 | 2′-5′-oligoadenylate synthetase 3, 100 kDa | 6.84E−21 |
| HLA-C | 3107 | Major histocompatibility complex, class I, C | 9.21E−21 |
| KSR1 | 8844 | Kinase suppressor of ras 1 | 1.92E−19 |
| CFB | 629 | Complement factor B | 5.48E−19 |
| ISG15 | 9636 | ISG15 ubiquitin-like modifier | 1.10E−18 |
| IFIH1 | 64135 | Interferon induced with helicase C domain 1 | 4.79E−18 |
| IFIT3 | 3437 | Interferon-induced protein with tetratricopeptide repeats 3 | 4.91E−18 |
| SPRR2C | 6702 | Small proline-rich protein 2C (pseudogene) | 3.18E−17 |
| DDX60 | 55601 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 2.97E−16 |
| HELZ2 | 85441 | Helicase with zinc finger 2, transcriptional coactivator | 6.21E−16 |
| MX2 | 4600 | MX dynamin-like GTPase 2 | 7.51E−16 |
| WARS | 7453 | Tryptophanyl-tRNA synthetase | 1.21E−15 |
| ICAM1 | 3383 | Intercellular adhesion molecule 1 | 1.91E−15 |
| PARP14 | 54625 | Poly (ADP-ribose) polymerase family, member 14 | 1.33E−14 |
| FABP5 | 2171 | Fatty acid binding protein 5 (psoriasis-associated) | 1.60E−14 |
| SAMD9 | 54809 | Sterile alpha motif domain containing 9 | 3.67E−14 |
| OAS1 | 4938 | 2′-5′-oligoadenylate synthetase 1, 40/46 kDa | 7.40E−14 |
| STAT1 | 6772 | Signal transducer and activator of transcription 1, 91 kDa | 1.96E−13 |
| LGALS3BP | 3959 | Lectin, galactoside-binding, soluble, 3 binding protein | 1.71E−12 |
| LGALS7 | 3963 | Lectin, galactoside-binding, soluble, 7 | 5.08E−12 |
| S100A8 | 6279 | S100 calcium binding protein A8 | 1.97E−11 |
| RSAD2 | 91543 | Radical S-adenosyl methionine domain containing 2 | 8.80E−11 |
| TRANK1 | 9881 | Tetratricopeptide repeat and ankyrin repeat containing 1 | 1.47E−10 |
| OASL | 8638 | 2′-5′-oligoadenylate synthetase-like | 3.64E−10 |
| STAT2 | 6773 | Signal transducer and activator of transcription 2, 113 kDa | 7.00E−10 |