Table 1. Demographic and clinical characteristics including baseline blood chemistry of patients with acute non–ST-elevation myocardial infarction divided into two groups having blood leukocyte count > 11,000/µL and ≤ 11,000/µL.
Variables | All patients (N = 585) |
Leukocyte count ≤ 11,000/µL (N = 397) |
Leukocyte count > 11,000/µL (N = 188) |
p-Value |
---|---|---|---|---|
Age (y) | 61 ± 9.6 | 61.3 ± 9.6 | 60.0 ± 9.4 | 0.223 |
Male gender, N (%) | 462 (79%) | 306 (77%) | 156 (82%) | 0.102 |
Systolic blood pressure (mm Hg) | 142.5 ± 29 | 143.3 ± 29 | 140.9 ± 28 | 0.383 |
Heart rate (beats/min) | 90 ± 23.8 | 87 ± 23 | 97 ± 24 | < 0.001 |
Prior myocardial infarction | 97 (16%) | 66 (17%) | 31 (16%) | 0.947 |
Risk factor profile, N (%) | ||||
Family history | 148 (25%) | 106 (27%) | 42 (22%) | 0.231 |
Smoker | 141 (24%) | 89 (22%) | 52 (27%) | 0.230 |
Hypertension | 423 (72%) | 287 (72%) | 136 (72%) | 0.990 |
Diabetes mellitus | 220 (38%) | 141 (35%) | 79 (42%) | 0.104 |
Dyslipidemia | 277 (47%) | 192 (48%) | 85 (45%) | 0.529 |
Lipid profile | ||||
Total cholesterol (mg/dL) | 188 ± 50 | 190 ± 49 | 184 ± 50 | 0.313 |
LDL-cholesterol (mg/dL) | 123 ± 42 | 124.3 ± 42 | 120 ± 42 | 0.420 |
HDL-cholesterol (mg/dL) | 37.8 ± 12 | 38.2 ± 12 | 36.8 ± 11 | 0.235 |
Triglyceride (mg/dL) | 142 ± 91 | 146 ± 93 | 133 ± 86 | 0.060 |
CK-MB (U/L) | 25 (3–523) | 23 (4–324) | 32 (3–523) | < 0.001 |
Troponin T > 0.03 µg/L | 512 (88.6) | 342 (86) | 170 (90) | 0.142 |
Creatinine (mg/dL) | 1.4 ± 0.9 | 1.38 ± 0.9 | 1.52 ± 1.1 | 0.014 |
Length of stay (d) | 8.77 ± 7.14 | 8.82 ± 6.7 | 8.68 ± 7.8 | 0.501 |
Coronary angiography, N (%) | 221 (38%) | 161 (40%) | 60 (32%) | 0.042 |
PCI, N (%) | 79 (13%) | 54 (13%) | 25 (13%) | 0.262 |
CABG, N (%) | 29 (5%) | 22 (5%) | 7 (3%) | 0.696 |
Medication at enrollment, N (%) | ||||
ACE inhibitor | 313 (53%) | 205 (51%) | 108 (57%) | 0.188 |
Beta-blocker | 373 (64%) | 273 (68%) | 100 (53%) | < 0.001 |
MACE, N (%) | 52 (9%) | 21 (5%) | 31 (16%) | < 0.001 |
Abbreviations: ACE, angiotensin-converting enzyme; CABG, coronary artery bypass grafting; CK-MB, creatine kinase-MB; MACE, major adverse cardiac event; PCI, percutaneous coronary intervention.
Continuous data presented as mean ± standard deviation or median (range) and categorical variables as number and percentages.