Table 2. Univariate predictors of cardiovascular events.
| Variables | HR (95% CI) | p-Value |
|---|---|---|
| Age (> 65 y) | 0.913 (0.50–1.63) | 0.759 |
| Male gender | 1.085 (0.54–2.17) | 0.818 |
| History of MI | 0.915 (042–1.96) | 0.820 |
| Risk factor profile | ||
| Family history | 0.774 (0.39–1.51) | 0.453 |
| Diabetes mellitus | 1.240 (0.70–2.17) | 0.453 |
| Hypertension | 0.701 (0.39–1.24) | 0.227* |
| Dyslipidemia | 1.089 (0.61–1.93) | 0.772 |
| Smoker | 0.749 (0.51–1.08) | 0.130* |
| Systolic blood pressure < 100 mm Hg | 0.853 (0.26–2.78) | 0.792 |
| Heart rate > 100 beats/min | 1.425 (0.80–2.54) | 0.229* |
| Lipid profile | ||
| Total cholesterol > 200 mg/dL | 1.202 (0.57–2.51) | 0.625 |
| HDL-cholesterol < 40 mg/dL | 0.780 (0.37–1.61) | 0.501 |
| LDL-cholesterol > 130 mg/dL | 1.210 (0.58–2.51) | 0.609 |
| Triglyceride > 150 mg/dL | 0.883 (0.37–2.10) | 0.779 |
| Creatinine > 1.5 mg/dL | 1.958 (1.10–3.47) | 0.022* |
| Leukocyte count > 11,000/µL | 3.178 (1.81–5.57) | < 0.001 |
| Medication at enrollment | ||
| Beta-blocker | 0.676 (0.38–1.17) | 0.167* |
| ACE inhibitor | 0.638 (0.36–1.11) | 0.116* |
Abbreviations: ACE, angiotensin-converting enzyme; CI, confidence interval; HR, hazard ratio; MI, myocardial infarction.
*
Variables with p value < 0.25 were entered into multivariate Cox regression analysis.