Table 4.
Results using different normal organ dose limits for subject #8
| Organ dose limits | Maximum activity (GBq) 90 Y-DOTA alone (given over multiple cycles) | Optimum percentage of maximum 90 Y activity to be given when adding MIBG | Acivity (GBq) of 131 I-MIBG that can be added without exceeding limits | Tumor dose (cGy): 90 Y-DOTA given alone | Tumor dose (cGy): 90 Y + 131 I | |
|---|---|---|---|---|---|---|
| Kidney | 2,300 | 4.9 | 75 | 33.3 | 1,006 | 2,499 |
| Marrow | 300 | |||||
| Kidney | 2,300 | 4.9 | 87 | 17.6 | 1,006 | 1,794 |
| Marrow | 200 | |||||
| Kidney | 2,700 | 5.8 | 80 | 30.8 | 1,180 | 2,565 |
| Marrow | 300 |