Table 3. Cut-off Values of ROTEM Parameters during CPB Rewarming to Predict Thrombocytopenia and Hypofibrinogenemia after CPB Weaning.
| ROTEM | Cutoff | Sensitivity | Specificity | PPV | NPV | AUC | SE | 95% CI | z statistic | P* | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Platelets < 100,000 /µl (n = 98) | EXTEM A10 | ≤ 42 | 74.2 | 73.7 | 87.8 | 52.8 | 0.768 | 0.0486 | 0.688-0.836 | 5.522 | < 0.0001 |
| EXTEM MCF | ≤ 53 | 77.6 | 59.0 | 82.6 | 51.1 | 0.723 | 0.0508 | 0.640-0.796 | 4.396 | < 0.0001 | |
| PLTEM A10 | ≤ 33 | 80.4 | 71.1 | 87.6 | 58.7 | 0.795 | 0.0484 | 0.717-0.860 | 6.094 | < 0.0001 | |
| PLTEM MCF | ≤ 44 | 90.8 | 48.7 | 81.7 | 67.9 | 0.738 | 0.0495 | 0.656-0.809 | 4.811 | < 0.0001 | |
| Fibrinogen < 150 mg/dl (n = 62) | FIBTEM A10 | ≤ 8 | 62.3 | 88.2 | 80.9 | 74.4 | 0.853 | 0.0310 | 0.783-0.908 | 11.403 | < 0.0001 |
| FIBTEM MCF | ≤ 9 | 67.7 | 85.5 | 79.2 | 76.5 | 0.849 | 0.0317 | 0.779-0.905 | 11.034 | < 0.0001 |
CPB: cardiopulmonary bypass, PPV: positive predictive value, NPV: negative predictive value, AUC: area under the curve, SE: standard error, CI: confidence interval. *Comparison to AUC of 0.5.