Table 2. Logistic regression model of metformin intolerance.
OR (95% CI) | p | |
---|---|---|
Age | 1.10 (1.08-1.12) | <0.001 |
Sex (Females vs Males) | 1.85 (1.33-2.57) | <0.001 |
Weight | 0.99 (0.98-1.00) | 0.064 |
Use of OCT1 inhibiting drugs | 1.64 (1.20-2.25) | 0.002 |
Two reduced-function OCT1 alleles | 2.41 (1.48-3.93) | <0.001 |
OR, odds ratio for intolerance. Logistic regression analysis included 205 intolerant and 1650 tolerant patients.