Table 2. Glucose, fructose and sorbitol levels for all subjects.

	All Subjects	Lean (n = 6)	Obese (n = 10)	DM (n = 9)	P *
Plasma Glucose	4.3 ± 0.1	4.3 ± 0.2	4.2 ± 0.2	4.5 ± 0.2	0.61
CSF glucose	2.5 ± 0.1	2.5 ± 0.1	2.6 ± 0.1	2.5 ± 0.1	0.65
CSF:plasma ratio	0.6 ± 0.04	0.6 ± 0.03	0.7 ± 0.1	0.6 ± 0.02	0.30
Cord glucose	3.2 ± 0.3	3.9 ± 0.2	2.5 ± 0.6	3.7 ± 0.2	0.58
Plasma Fructose
Mean	0.01 ± 0.001	0.008 ± 0.004	0.012 ± 0.001	0.007 ± 0.002	0.22
Median (IQR)	0.009 (0.003, 0.015)	0.006 (0.003, 0.016)	0.01 (0.01, 0.015)	0.003 (0.003, 0.014)
CSF Fructose
Mean	0.17 ± 0.01	0.18 ± 0.02	0.18 ± 0.02	0.14 ± 0.01	0.16
Median (IQR)	0.17 (0.11, 0.19)	0.19 (0.12, 0.21)	0.18 (0.13, 0.20)	0.14 (0.11, 0.18)
CSF:plasma ratio
Mean	27 ± 5	34 ± 14	16 ± 4	34 ± 7	0.47
Median (IQR)	17 (11, 47)	32 (9, 60)	13 (12, 17)	39 (10, 55)
Cord fructose
Mean	0.009 ± 0.001	0.01 ± 0.004	0.008 ± 0.001	0.009 ± 0.001	0.65
Median (IQR)	0.009 (0.006, 0.01)	0.01 (0.005, 0.01)	0.007 (0.006, 0.01)	0.009 (0.007, 0.01)
Plasma sorbitol
Mean	0.02 ± 0.00	0.03 ± 0.01	0.02 ± 0.01	0.02 ± 0.00	0.97
Median (IQR)	0.02 (0.01, 0.03)	0.02 (0.01, 0.04)	0.02 (0.01, 0.03)	0.02 (0.015, 0.02)
CSF sorbitol
Mean	0.17 ± 0.02	0.15 ± 0.02	0.17 ± 0.02	0.14 ± 0.02	0.89
Median (IQR)	0.15 (0.12, 0.17)	0.15 (0.10, 0.18)	0.15 (0.12, 0.19)	0.15 (0.11, 0.17)
CSF:plasma ratio
Mean	9.6 ± 1	9.8 ± 6.1	10.5 ± 2.4	8.5 ±4.3	0.92
Median (IQR)	8.5 (5, 15)	8.2 (6, 16)	8.2 (4, 17)	8.7 (5, 12)
Cord sorbitol
Mean	0.13 ± 0.02	0.08 ± 0.03	0.17 ± 0.04	0.12 ± 0.02	0.48
Median (IQR)	0.12 (0.08, 0.16)	0.11 (0.00, 0.13)	0.14 (0.09, 0.25)	0.13 (0.08, 0.16)

* P values across groups; Glucose, fructose, and sorbitol in mmol/l; Unless otherwise noted, data presented as mean ± SE