Table 2. Association between breast cancer diagnosis and clinically diagnosed anxiety and depression among matched cases and controls, Nationwide inpatient sample, 2006–2009 ⁺ .

	Cases	Controls	Unadjusted	Adjusted	Fully adjusted
	N = 4,164	N = 4,164	OR (95% CI)	OR (95% CI) 1	OR (95% CI) 2
Diagnosed Depression
No	3,809	3,585	Ref	Ref	Ref
Yes	355	579	0.58 (0.50–0.66)**	0.58 (0.48–0.70)***	0.63 (0.52–0.77)***
Diagnosed Anxiety
No	3,992	3,918	Ref	Ref	Ref
Yes	172	246	0.67 (0.55–0.83)**	0.65 (0.50–0.84)**	0.68 (0.52–0.90)**
Race/Ethnicity
White	2,375	2,387	Ref	Ref	Ref
Black	407	381	0.95 (0.81–1.14)	1.01 (0.84–1.20)	1.08 (0.88–1.31)
Hispanic	203	229	1.23 (0.97–1.55)	0.80 (0.63–1.01)	0.79 (0.61–1.02)
Other	167	163	1.01 (0.79–1.30)	0.97 (0.76–1.26)	0.82 (0.63–1.08)
Residential Income
Q1-Lowest	958	1,133	Ref		Ref
Q2	977	1,138	1.01 (0.89–1.14)		0.97 (0.82–1.16)
Q3	963	977	1.15 (1.07–1.30)		0.97 (0.81–1.18)
Q4-Highest	1,174	812	1.73 (1.52–1.96)		1.36 (1.12–1.64)***
Insurance Type
Private	2,055	1,711	Ref		Ref
Medicare	1,554	1,790	0.51 (0.44–0.59)**		0.58 (0.47–0.70)**
Medicaid	333	336	0.82 (0.69–0.97)*		0.95 (0.75–1.21)*
Other	222	327	0.57 (0.47–0.68)*		0.62 (0.48–0.80)*
Residential Region
Large metro	2,237	1,974	Ref		Ref
Small metro	1,059	1,165	0.79 (0.72–0.88)*		0.87 (0.75–1.01)
Micropolitan	423	538	0.68 (0.59–0.79)*		0.72 (0.58–0.91)*
Not metro or micro	277	354	0.68 (0.58–0.82)*		0.72 (0.58–0.91)*

¹Adjusted for race/ethnicity

²Adjusted for race/ethnicity, residential income, insurance and residential region

*** p-value <0.001;

** p-value <0.01,

* p-value <0.05

⁺Cell values may not add up to total due to missing data. There were 1012 cases and 1014 controls with missing data on race/ethnicity, and 92 cases and 104 controls with missing data on residential income.