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Morphology of cultured cells with overexpressed BVR. (A) HEK cell transfected with an EGFP-BVR fusion plasmid shows a flattened morphology atypical of the parent cell line. Adapted from (Maines, 2005). (B) Similarly, HeLa cells transfected at low efficiency with a human BVR expression plasmid and analyzed by immunohistochemistry with antibody against BVR are apparently enlarged relative the surrounding lawn of untransfected cells.
