Table 1.
Demographic and clinical features of the participants whose sera were examined with individual RT-qPCR assays in the training set and the validation seta.
| Variables | NDC (n = 123) | AD (n = 127) | MCI (n = 30) | VD (n = 30) | P-value (NDC, AD & NDC, MCI) |
|---|---|---|---|---|---|
| Age | 79.5 ± 6.8 | 79.3 ± 8.9 | 81.1 ± 6.8 | 82.1 ± 6.8 | 0.8951b; 0.2348b |
| Age group | 0.2598c; 0.3876c | ||||
| <65 years | 4 (3.3%) | 8 (6.3%) | 2 (6.7%) | 1 (3.3%) | |
| ≥65 years | 119 (96.7%) | 119 (93.7%) | 28 (93.3%) | 29 (96.7%) | |
| Gender | 0.5412c; 0.0895c | ||||
| Male | 65 (52.8%) | 72 (56.7%) | 21 (70.0%) | 26 (86.7%) | |
| Female | 58 (47.2%) | 55 (43.3%) | 9 (30.0%) | 4 (13.3%) | |
| Years of education | 9.5 ± 5.4 | 8.4 ± 5.2 | 11.4 ± 4.1 | 10.5 ± 5.3 | 0.2017b; 0.1687b |
| MMSE | 27.2 ± 1.3 | 11.5 ± 7.7 | 25.6 ± 2.3 | 8.7 ± 9.0 | <0.0001b; <0.0001b |
aData are presented as the means ± SD, bStudent's t-test, and ctwo-sided λ 2 test.