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. 2015 May 13;7(5):2404–2427. doi: 10.3390/v7052404

Figure 6.

Figure 6

Cytokine levels in serum collected from UV-12 treated AG129 mice. Groups of AG129 mice received the first treatment dose of 100 mg/kg of UV-12 or vehicle control 1 h before infection with DENV2 at a dose of ~1LD90. Treatment continued three times daily at 8 h intervals until harvest at 72 or 92 h post infection followed by analysis for levels of G-CSF, GM-CSF, IFN-γ, IL-1α, IL-1β, IL-2, IL-3, IL-4, IL-5, IL-6, IL-10, IL-12 (p40), IL-12 (p70), IL-13, IL-17A, KC, MCP-1 (MCAF), MIP-1α, MIP-1β, RANTES and TNF-α via a multiplex assay. Statistical significance is indicated above sets of data where the p value <0.05 (*), <0.01 (**), <0.001 (***), and <0.0001 (****).