Table 1.
Varenicline cohort (n=69 757) | Non-treated cohort* (n=7 847 679) | |
---|---|---|
Characteristics at baseline 2006 | ||
Women | 43 861 (62.9) | 3 964 263 (50.5) |
Men | 25 896 (37.1) | 3 883 417 (49.5) |
Age distribution: | ||
<20 | 408 (0.6) | 982 116 (12.5) |
20-29 | 3744 (5.4) | 1 084 733 (13.8) |
30-39 | 9226 (13.2) | 1 222 610 (15.6) |
40-49 | 17 375 (24.9) | 1 221 021 (15.6) |
50-59 | 21 480 (30.8) | 1 170 086 (14.9) |
60-69 | 14 447 (20.7) | 1 022 055 (13.0) |
≥70 | 3077 (4.4) | 1 143 656 (14.6) |
Psychiatric diagnoses: | ||
Pre-existing psychiatric diagnosis† | 9391 (13.5) | 484 536 (6.2) |
Lifetime alcohol misuse diagnosis‡ | 5562 (8.0) | 197 988 (2.5) |
Lifetime drug misuse diagnosis‡ | 2633 (3.8) | 80 535 (1.0) |
Lifetime nicotine dependence diagnosis‡ | 2379 (3.4) | 19 392 (0.3) |
Characteristics during follow-up (22 November 2006 to 31 December 2009) | ||
Inpatient or outpatient care: | ||
New psychiatric conditions | 3213 (4.6) | 168 869 (2.2) |
Anxiety conditions | 1816 (2.6) | 88 905 (1.1) |
Mood conditions | 1717 (2.5) | 84 931 (1.1) |
Psychoses | 320 (0.5) | 24 384 (0.3) |
Suicidal behaviour | 657 (0.9) | 26 093 (0.3) |
Crimes: | ||
Convicted of any crime | 2256 (3.2) | 204 508 (2.6) |
Suspected of any crime | 3782 (5.4) | 311 914 (4.0) |
Transport accidents and traffic offences: | ||
Transport accident | 989 (1.4) | 108 612 (1.4) |
Convicted of traffic offence | 328 (0.5) | 36 271 (0.5) |
Suspected of traffic offence | 440 (0.6) | 46 572 (0.6) |
*All people in cohort who were not treated with varenicline during follow-up.
†Diagnosed before 1 November 2006.
‡Diagnosed between 1 January 1987 and 31 December 2009.