Table 2.
Hemodialysis cohort overall and by cognitive impairment classification
| Total N=38 (%) |
Normal – Mild N = 13 (%) |
Moderate-Severe N = 25 (%) |
P Value | |
|---|---|---|---|---|
| Age | ||||
| Mean ± SD | 65.9 ± 9.0 | 68.7 ± 10.1 | 64.5 ± 8.2 | 0.18 |
| Race | 0.23* | |||
| American Indian/Alaskan Native | 2 (5.3) | 1 (7.7) | 1 (4.0) | |
| African American | 25 (65.8) | 6 (46.2) | 19 (76.0) | |
| White | 11 (28.9) | 6 (46.2) | 5 (20.0) | |
| Gender | 1.00* | |||
| Female | 5 (13.2) | 3 (15.4) | 3 (12.0) | |
| Male | 33 (86.8) | 11 (84.6) | 22 (88.0) | |
| Duration of Dialysis (years) | ||||
| Mean ± SD | 4.6 ± 4.5 | 3.8 ± 5.0 | 5.0 ± 4.2 | 0.43 |
| Years of Education | 0.49* | |||
| No College | 24 (63.1) | 7 (55) | 17 (68) | |
| College and beyond | 14(36.8) | 6 (46) | 8 (32) | |
| Comorbidities | ||||
| (+) HTN | 38 (100) | 13 (100) | 25 (100) | n/a |
| (+) DM | 18 (47.4) | 5 (38.5) | 13 (52.0) | 0.43** |
| (+) CHF | 14 (36.8) | 2 (15.4) | 12 (48.0) | 0.08* |
| (+) CAD | 13 (34.2) | 4 (30.8) | 9 (36.0) | 1.00* |
| (+) PVD | 5 (13.2) | 0 (0) | 5 (20.0) | 0.14* |
| (+) Cirrhosis | 0 (0.0) | 0 (0.0) | 0 (0.0) | n/a |
| (+) Stroke | 4 (10.5) | 0 (0.0) | 4 (16.0) | 0.28* |
| Hospital Admissons | 2.0±2.2 | 1.8±2.2 | 2.1±2.3 | 0.69 |
| Cause of ESRD | 0.01* | |||
| DM | 14 (36.8) | 2 (15.4) | 12 (48.0) | |
| HTN | 13 (34.2) | 3 (23.1) | 10 (40.0) | |
| GN | 5 (13.2) | 3 (23.1) | 2 (8.0) | |
| Other | 6 (15.8) | 5 (38.4) | 1 (4.0) | |
| Participants on ESA | 26 (68.4) | 10 (76.9) | 16 (64.0) | 0.49 |
| Laboratory Data | ||||
| Hemoglobin (g/l) ± SD | 109.2 ± 11.9 | 110.5 ± 16.0 | 108.4 ± 9.7 | 0.63 |
| Albumin (g/l) ± SD | 39.1 ± 3.9 | 39.7 ± 3.8 | 38.6± 4.1 | 0.48 |
| URR (%)± SD | 75.6 ± 4.3 | 77.6 ± 3.2 | 74.6 ± 4.5 | 0.04 |
| Kt/V± SD | 1.5 ± 0.2 | 1.6 ± 0.2 | 1.5 ± 0.2 | 0.09 |
T-test was used to compares groups except when marked by * for Fisher exact test and by ** when chi-squared test was used. HTN is hypertension, DM is Diabetes Mellitus, CHF is congestive heart failure, CAD is coronary artery disease, PVD is peripheral vascular disease, GN is glomerulonephropathy, ESA is erythropoietin stimulating agents (darbepoetin or epoetin). Hospital admissions refers to admission in the one year prior to the date of the cognitive assessment. Laboratory data shown in mean ± SD. URR is the urea reduction ratio, and Kt/V, is a measure of dialysis adequacy.