Table 1.

Characteristics of the control and HFD dams

Variable	Control (n=14)	HFD (n=37)	p value
Donors
Weight (g)	20.56±0.24	36.42±0.86	<0.0001
2 h GTT, AUC (mmol/l×min) (n=10 each group)	785±31	1,262±70	<0.0001
Fasting blood glucose (mmol/l) (n=10 each group)	5.47±0.12	5.33±0.18	0.5614
Leptin (μg/l) (n=10 each group)	2.68±0.25	57.14±5.35	<0.0001
Recipients
n	21	25
Pre-pregnancy
Weight (g)	27.04±0.75	43.37±0.77	<0.0001
2 h GTT, AUC (mmol/l×min) (n=10 each group)	747±13	1,198±104	0.0082
Fasting blood glucose (mmol/l) (n=10 each group)	4.88±0.26	4.37±0.33	0.3234
Leptin (μg/l) (n=10 each group)	4.47±1.18	19.65±3.19	0.0017
E12.5
Fasting blood glucose (mmol/l) (n=10 each group)	5.74±0.28	7.09±0.01	0.0522
Leptin (μg/l) (n=10 each group)	8.99±1.77	33.34±9.63	0.0167
E17.5
Fasting blood glucose (mmol/l) (n=10 each group)	6.41±0.65	6.07±0.41	0.6607
Leptin (μg/l) (n=10 each group)	9.01±0.75	41.9±7.91	0.0251

Data are presented as means±SEM