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. Author manuscript; available in PMC: 2016 Jan 15.
Published in final edited form as: Cell. 2015 Jan 15;160(0):88–104. doi: 10.1016/j.cell.2014.12.022

Figure 4. Increased browning in DKO mice.

Figure 4

A) Ucp-1 gene expression in BAT and WAT depots extracted from 12 week-old POMC-1B, POMC-TC, DKO and floxed control mice. b) Interscapular BAT temperatures. c–e) Histology (H&E), immunoblotting and UCP-1 immunohistochemistry in inguinal WAT (IngWAT). f–g) Browning gene expression in ingWAT or BAT and h) body weights. Data are means ± SEM and are representative of 3 independent experiments; significance determined using a) one-way, or, f–g) two-way ANOVA.