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. 2015 May 4;7(5):1363–1379. doi: 10.1093/gbe/evv068

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© The Author(s) 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 6.— — Duplications and losses of PA28 copies in chordates. (A) Synopsis of PA28 isoform distribution in chordates. Sequences similar to PSME1 (REGα/PA28α), PSME2 (REGβ/PA28β), and PSME3 (REGγ/PA28γ) were identified by reciprocal Blast searches. Black squares: E-values lower than e⁻⁸⁰. ⊠: homologous sequences not found. Taxonomy is indicated on the left. Chordate taxa showing a single isoform are colored in red and the names of the corresponding species are grayed. (B) PSME phylogeny in chordates. MrBayes and PhyML analysis of the MSA shown in supplementary figure S4, Supplementary Material online, produced the same tree topology. PP and bootstrap proportion are shown only for nodes informative for the duplication history. Short branches that link PSME3 orthologs are signaled by arrowheads and long branches that connect PSME3 to its paralogs, by arrows. Species abbreviation corresponds to species listed in (A).