Fig. 1.

Effect of local high-dose irradiation on tumor growth and expression of miR-545 and Ku70 in mice bearing Lewis lung carcinoma tumor. Seven days after C57BL/6 mice transfected with Lewis lung cancer cell lines, tumors were irradiated with a single dose of 12 Gy/1f/1d, whereas control mice received no radiotherapy. (a) Growth of tumor in irradiated mice. (b) Expressions of miR-545 and (c) Ku70 were determined by using Quantitative Real-Time PCR in tumors. The results were represented as mean ± SD. ^* P < 0.05 compared with control