Fig. 9.

Population sizes of platelet-derived growth factor receptor α- and myelin basic protein-immunoreactive cells derived from human oligodendrocyte progenitor cell transplant. a Differentiation patterns at 6 weeks and 3 months after transplantation in two brain regions (corpus callosum versus transplantation area in cortex) in impact acceleration (IA) animals. b Differentiation patterns in the same two locations based on experimental history (IA versus sham) at 3 months post-transplantation. In (a), IA rats at 3 months have more myelin basic protein (MBP) (+) and fewer platelet-derived growth factor receptor (PDGFR)α(+) transplant-derived oligodendrocytes than at 6 weeks post-transplantation; counts were performed at the transplantation site. In (b), IA rats at 3 months have more transplant-derived MBP(+) oligodendrocytes compared to sham in the corpus callosum (cc). *P < 0.05