Figure 4.

(A) Telomere length by stage at diagnosis. Patients with metastatic (stage IV) disease at presentation had longer TL than those who had localised disease or stages 1–3 with P=0.02. (B) Telomere length by age at diagnosis. The data were analysed in a dichotomous manner based on age of 60 years. The mean TL of the younger patients was longer than the older patients (P=0.027). (C) Overall survival of patients based on TL. The OS for patients was determined as the period from time of diagnosis of metastatic disease to death. There was no difference in OS in those patients with TL>median compared with those with TL<median, with a HR of 1.11 (P=0.30).