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. 2014 Dec 16;112(2):329–337. doi: 10.1038/bjc.2014.589

Figure 7.

Figure 7

Model of the supposed molecular mechanism. Pan-HDACi (LBH589) can deplete BCL-xL and inhibit C/EBPɛ induction by ATRA. Consequently, cells show caspase activation and undergo cell death.