Table 2. Adverse events (n=42).

Toxicities	All grade, n (%)	Grade 3, n (%)	Grade 4, n (%)
Laboratory
Neutropenia	26 (61.9)	10 (23.8)	2 (4.8)
Anaemia	23 (54.8)	2 (4.8)	0
Thrombocytopenia	5 (11.9)	2 (4.8)	0
AST/ALT elevation	4 (9.5)	2 (4.8)	0
Creatinine elevation	6 (14.3)	1 (2.4)	0
Non-laboratory
Nausea	25 (59.5)	1 (2.4)	0
Anorexia	24 (57.1)	1 (2.4)	0
Constipation	12 (28.6)	0	0
Mucositis	7 (16.7)	0	0
Fatigue	36 (85.7)	1 (2.4)	0
Myalgia	6 (14.3)	0	0
Oedema	7 (16.7)	1 (2.4)	0
Infection	6 (14.3)	2 (4.8)	0
Thromboembolic event	2 (4.8)	1 (2.4)	1 (2.4)

Abbreviations: ALT=alanine aminotransferase; AST=aspartate aminotransferase.