Table 2. Comparison between MBC diagnosed in the Western countries and Asian countries.
| Western series | Asian series | P-value | |
|---|---|---|---|
| Mean age in years (range) |
61 (27–96) |
57 (32–85) |
0.017 |
|
Type of surgery | |||
| Breast conserving surgery | 95 (50) | 21 (24) | <0.001 |
| Mastectomy |
96 (50) |
67 (76) |
|
|
Tumour Size | |||
| TNM pT1 | 46 (24) | 16 (19) | 0.797 |
| TNM pT2 | 100 (52) | 47 (55) | |
| TNM pT3&4 |
45 (24) |
22 (26) |
|
|
Tumour subtypes | |||
| Spindle cell | 95 (34) | 21 (24) | 0.001 |
| Squamous | 47 (17) | 30 (34) | |
| Mixed squamous and spindle | 36 (13) | 13 (15) | |
| Matrix producing | 80 (29) | 24 (27) | |
| Fibromatosis-likea |
18 (7) |
0 (0) |
|
|
Associated conventional carcinoma | |||
| Yes | 147 (58) | 73 (88) | <0.001 |
| No |
105 (42) |
10 (12) |
|
|
Invasive carcinoma grade | |||
| 1 | 4 (1) | 2 (2) | 0.009 |
| 2 | 71 (26) | 7 (10) | |
| 3 |
196 (73) |
64 (88) |
|
|
LN stage | |||
| 1 (LN negative) | 131 (73) | 49 (68) | 0.118 |
| 2 (1–3 positive nodes) | 35 (19) | 12 (16) | |
| 3 (>3 positive nodes) |
14 (8) |
12 (16) |
|
|
Lymphovascular invasion | |||
| Negative | 150 (78) | 68 (81) | 0.596 |
| Positive |
42 (22) |
16 (19) |
|
| Radiotherapy |
123 (68) |
30 (50) |
0.038 |
| Chemotherapy | 114 (61) | 28 (81) | 0.022 |
a
Fibromatosis-like is a recently recognized subtype is a low grade spindle carcinoma diagnosed mainly in Nottingham a part of a consultation service. Follow-up was available for two cases only; therefore, they were grouped with spindle MBC.