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. 2015 Mar 17;6(2):e02481-14. doi: 10.1128/mBio.02481-14

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Copyright © 2015 Romano et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-ShareAlike 3.0 Unported license, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original author and source are credited.

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FIG 3 — Host genotype and community composition modulate FMO activity and serum TMAO levels. (A and B) Serum TMAO levels (A) and total hepatic FMO enzymatic activity levels (B) measured in adult female C57BL/6J and NMRI mice colonized with the “core plus C. sporogenes” community and with the “core plus all” community(average plus SEM; 3 to 6 animals in each experimental group). Significance was calculated by an unpaired two-tailed Student’s t test as follows: *, P value of <0.05; ****, P value of <0.0001.