TABLE 1.
Ape | Code | Date of birth (mo/day/yr) | Virus strain | Yr infected | Duration of infection (yr) | Plasma sampling date(s) (mo/day/yr) | CD4+ T cell count (cells/μl)a | Viral load (RNA copies/ml) | SIVcpz- ANT infectionc | Virus- specific antibodiesd | HIV vaccine history | Reference |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Marc | C487 | 9/6/81 | HIV-1/LAV | 1984 | 30 | 11/8/11 | 1,154 | <50 | + | None | 21 | |
Artica | C544 | 2/13/79 | HIV-1/LAV | 1986 | 28 | 11/10/11 | 1,153 | 4,794 | + | None | 23 | |
Joye | C542 | 2/13/79 | HIV-1/LAV | 1986 | 28 | 11/10/11 | 2,529 | 337 | NDe | LAV env | 23 | |
Tika | C534 | 10/3/78 | HIV-1/NC | 1997 | 17 | 11/10/11 | 4 | 244,324 | + | None | 22 | |
Debbie | X0284 | 9/23/85 | SIVcpzANT | 1996 | 18 | 1/21/10 | NA | ND | ND | ND | None | 20 |
10/26/10 | NA | 26,397 | + | + | ||||||||
6/28/11 | NA | ND | ND | ND | ||||||||
Cotton | X0115 | 4/10/77 | HIV-1/IIIB | NAf | >18 | 5/21/02 | NA | 77,142 | ND | ND | NA | 20 |
SIVcpzANT | 1996 | 9/25/12 | 229 | 1,440,622 | + | + | ||||||
11/25/14 | 220b | 861,000 | ND | ND | ||||||||
Bucky | NA | NA | NA | NA | NA | 11/10/11 | 1,016 | <50 | + | NA | NA | |
Josie | NA | 5/18/81 | NA | NA | NA | 11/10/11 | 516 | <50 | + | NA | NA |
CD4+ T cell counts were performed using blood collected in September 2010 unless otherwise noted.
The CD4+ T cell count was performed using blood collected in November 2014.
+, SIVcpzANT-specific amplification and sequence confirmation.
+, antibody reactivity determined using Western blot analysis (see Fig. S1 in the supplemental material).
ND, not done.
NA, not available.