Table 2A. Repeat screening uptake by invitation round: multivariable logistic regression results of sociodemographic and previous screening episode factors.

	R2		R3
	OR	95% CI	OR	95% CI
Sociodemographics
Men	1.00 (ref.)		1.00 (ref.)
Women	1.03	0.97–1.10	0.98	0.91–1.05
IMD score (0–80)	0.98***	0.98–0.99	0.99***	0.98–0.99
Age at second invitation (62–70)
62–63	1.00 (ref.)		—
64–65	1.05	0.99–1.13	—
66+	0.99	0.88–1.11	—
Age at third invitation (63–72 years)
64–65	—		1.00 (ref.)
66–67	—		0.94	0.88–1.01
68+	—		0.84**	0.74–0.95
Previous screening episode factors
Kit return – ⩽28 days	1.00 (ref.)		1.00 (ref.)
Kit return – >28 days	0.60***	0.56–0.64	0.69***	0.64–0.74
Weak positives – none	1.00 (ref.)		1.00 (ref.)
Weak positives – one or more	0.70***	0.57–0.85	0.70*	0.56–0.88
Definitive gFOBt result – normal	1.00 (ref.)		1.00 (ref.)
Definitive gFOBt result – abnormal	0.12***	0.06–0.23	0.27***	0.21–0.35
Spoilt kit – none	1.00 (ref.)		1.00 (ref.)
Spoilt kit – one or more	0.73	0.52–1.03	0.71*	0.52–0.98
Weak positive × definitive result	3.29**	1.54–7.06	—
Previous uptake subgroups
Consistent Screeners	—		1.00 (ref.)
Late Entrants	—		0.21***	0.19–0.23
Dropouts	—		0.09***	0.08–0.10
Weak positive × previous uptake	—		1.40***	1.16–1.67

Abbreviations: CI=confidence interval; gFOBt=guaiac fecal occult blood test; IMD=index of multiple deprivation; OR=odds ratio; ref.=reference category; R2=second biennial invitation round; R3=third biennial invitation round.

*P<0.05; **P<0.01; ***P<0.001.