Table 3. Deregulation of genes and miRNA.
| Gene/miRNA | Expression in group B (low) (vs group A (high)) | Log2 (fold change) | Fold change |
|---|---|---|---|
| FZD5 | Upregulation | 2.5188 | 5.7312 |
| TMEM92 | Upregulation | 3.9888 | 15.8762 |
| HNF1B | Upregulation | 1.2885 | 2.4428 |
| Hsa-mir-23a | Downregulation | 2.4 | 5.278 |
| Hsa-mir-24 | Downregulation | 2.2 | 4.5947 |
Abbreviations: miRNA=microRNA.
FZD5 is 2.5-fold, TMEM92 is 4.0-fold and HNF1B is 1.3-fold upregulated in group B. MiR-24 and miR-23a are 2.4- and 2.2-fold, respectively, downregulated in group B cell lines. (The deregulation is calculated as the fold change of logarithm to the base 2 (log2(FC)). Hsa-miR-24 targets for all three genes, TMEM92, HNF1B and FZD5. In addition to hsa-miR-24, FZD5 is also targeted by hsa-miR-23a.