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. 2014 Dec 23;112(3):468–474. doi: 10.1038/bjc.2014.633

Table 3b. Multivariable analysis for recurrence; association of CIS, substaging, tumour size, tumour pattern, lymphovascular invasion and gender with time to recurrence.

  Hazard ratio and 95% CI P
Substaging (T1a) 0.64 (0.37, 1.14) 0.13
CIS (No) 0.68 (0.38, 1.21) 0.19
Size (<3 cm) 0.59 (0.34, 1.01) 0.06
Pattern (papillary) 1.12 (0.53, 2.37) 0.78
Lymphovascular invasion (yes) 2.16 (0.71, 6.59) 0.18
Gender (male) 0.81 (0.36, 1.81) 0.60
Age (<70 years) 0.50 (0.29, 0.87) 0.01

Abbreviations: CI=confidence interval; CIS=carcinoma in situ. P<0.05 represent statistically significant values (shown in bold).