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. 2015 Jan 13;112(3):523–531. doi: 10.1038/bjc.2014.660

Figure 3.

Figure 3

Hypermethylated phenotype in NETs. In A, the distribution of tumours according to the number of methylated genes detected in tumour tissue is given. Open bars represent cases with methylated MGMT; solid bars represent cases with non-methylated MGMT. In B, overall survival curves from diagnosis are compared between patients with tumours containing ⩽3 methylated genes (group 1) and those with tumours containing >3 methylated genes (group 2). The difference is statistically significant (log-rank test, P=0.017). In C, overall survival curves from diagnosis are compared for the subset of patients with tumours containing >3 methylated genes according to their MGMT status (group 1: methylated MGMT, group 2: non-methylated MGMT). The difference is not statistically significant.