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. 2015 Jan 13;112(3):523–531. doi: 10.1038/bjc.2014.660

Table 1. MGMT status in 107 neuroendocrine tumours.

    Tumour location
Histological grade
  All patient (n=107) Pancreas (n=62) GI tract (n=33) Lung (n=5) Other (n=7) G1 (n=41) G2 (n=57) G3 (n=9)
MGMT promoter methylation, MS-PCR P   0.11       0.17  
 Non-interpretable 8 7 0 0 1 6 1 1
 Non-methylated 87 51 27 5 4 32 48 7
 Methylated 12 4 6 0 2 3 8 1
MGMT promoter methylation, pyrosequencing P   0.41       0.12  
 Non-interpretable 8 7 0 0 1 6 1 1
 Non-methylated 75 40 27 1 4 29 41 5
 Methylated 24 15 6 4 2 6 15 3
MGMT protein expression, immunohistochemistry P   0.45       0.64  
 Non-interpretable 18 12 4 2 0 8 10 0
 Positive 60 32 22 2 4 24 30 6
 Negative 29 18 7 1 3 9 17 3

Abbreviations: GI=gastrointestinal; MGMT=O6-methylguanine-DNA methyltransferase; MS-PCR=methyl-specific PCR.