Table 2. Association of variables with progression of carcinoid heart disease.
| Variable | Progression of carcinoid heart disease (n=13) | No progression of carcinoid heart disease (n=95) | P-value |
|---|---|---|---|
| Symptomatic deteriorationa | 11 (85%) | 5 (5%) | <0.001 |
| NT-proBNP progressionb | 8 (62%) | 24 (31%) | 0.04 |
| Plasma 5-HIAA progressionb | 6 (46%) | 14 (18%) | 0.035 |
| Radiological progressionc | 4 (31%) | 35 (37%) | 0.461 |
a
>50% increase in the number of daily flushing episodes or bowel movements compared with the previous visit.
b
>50% increase from the baseline value.
c
in accordance with RECIST (Response Evaluation Criteria in Solid Tumors) guidelines. Significant P-values (<0.05) are indicated in bold.