Table 1. Clinical and demographic details of the subjects.
| Group 1 surgery only (n=16) | Group 2 standard chemotherapy (n=32) | Group 3 anti-VEGF therapy (n=20) | P-value | |
|---|---|---|---|---|
| Age (years) | 71.2 (9.3) | 70.9 (7.9) | 70.7 (7.9) | 0.988 |
| Sex male/female (n) | 9/7 | 18/14 | 10/10 | 0.895 |
| BMI (kg m−2) | 28.4 (3.1) | 27.7 (2.6) | 26.2 (2.4) | 0.041 |
| Systolic blood pressure (mm Hg) | 121 (13) | 123 (9) | 122 (10) | 0.876 |
| Diastolic blood pressure (mm Hg) | 74 (8) | 75 (10) | 74 (7) | 0.732 |
| Dukes' stage (A/B/C/D) (n) | 9/5/1/1 | 2/13/8/9 | 0/5/11/4 | <0.001 |
| Major tumour site (colon/rectum)(n) | 12/4 | 22/10 | 10/10 | 0.239 |
| Tumour size (mm) | 37 (17) | 47 (24) | 43 (17) | 0.282 |
| Number of nodes excised (n) | 10.5 (8.5–12) | 12 (8.25–18.7) | 11.5 (10.25–18.75) | 0.321 |
Data are mean (s.d.), median (interquartile range), absolute number (n) or percentage. Analysed by ANOVA, Kruskal–Wallis or χ2 as appropriate.